IMPACT OF CAMEL MILK AND ITS PROTEIN FRACTIONS ON DIABETES IN ALBINO MALE RATS

doi:10.21608/mjard.2023.296029

IMPACT OF CAMEL MILK AND ITS PROTEIN FRACTIONS ON DIABETES IN ALBINO MALE RATS

Document Type : Original Articles

10.21608/mjard.2023.296029

Abstract

In this study Forty-eight pathogen-free adult male albino rats weighing
(120±10 g) aged 4-6-week-old were divided into 6 groups, T1 as negative
control (normal group; T2 as positive control (diabetic group; T3 diabetic
group supplemented with camel milk; T4 diabetic group supplemented with
camel milk whey proteins; T5 diabetic group supplemented with Diamicron
drug and T6 diabetic group supplemented with camel casein. The results
revealed a significant difference (P < 0.05) between diabetic group (T2) and
treated groups T3, T4 and T5. However, there was no significant difference
between the treatments T6 and diabetic group (T2). Moreover, T3, T4 and
T5 reduced blood glucose with no significant differences when compared to
normal group (T1). There was an effect of treatments (T3, T4 and T5 (P <
0.05) on body weight gain. Liver functions (ALT and AST) and kidney
function (creatinine) replenished to almost the normal status at treatment
with camel milk, camel milk whey proteins and drug treated groups. The
histopathological sections of pancreatic tissues from groups T3, T4 and T5
showed no presence of degeneration, inflammatory cells, and necrosis. The
data obtained in this study clearly show that camel milk and camel milk
whey proteins significantly reduced blood glucose level and can be used as
adjunctive therapy in type 2 diabetes mellitus.

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